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In addition, reductions in systolic function [94], ejection fraction [95], increased systemic arterial resistance [96], as well as structural abnormalities [95, 96] have all been observed in rodent models exposed to aerosol with nicotine

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The toxic chemicals present in cigarette smoke, such as nicotine and carbon monoxide, can disrupt the delicate balance of hormones and enzymes necessary for the production of healthy sperm

Therefore, researchers must rely on self-reported data from their subjects and trust that the information they are providing is reliable and that they were using condoms correctly